Description
Product Characteristics:
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit, which is the product of this gene, and the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
Subcellular location: Cell membrane
Synonyms: subfamily M subunit alpha-1, BK channel, BKCA alpha, BKCA alpha subunit, BKTM, Calcium-activated potassium channel, Calcium-activated potassium channel subunit alpha-1, Drosophila slowpoke like, hSlo, KVCAalpha, KCa1.1, KCMA1_HUMAN, KCNMA, KCNMA1, Maxi K channel, Maxi Potassium channel alpha, MaxiK, SAKCA, SLO alpha, SLO, Slo homolog, Slo-alpha, Slo1, Slowpoke homolog.
Target Information: MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit, which is the product of this gene, and the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]